MT674

BIOMATERIALS

Introduction to biomaterials; need for biomaterials; classification of biomaterials and medical devices; Metallic implant materials, ceramic implant materials, polymeric implant materials, composites as biomaterials; Orthopedic, dental and other applications.

  

Biomaterials preparation and characterization; Mechanical and physical properties evaluation of biomaterials; Nanomaterials and nanocomposites for medical applications; New and novel materials for biomaterial applications.

  

Biological responses to materials; In-vitro and In-vivo evaluation; Dissolution study, cytotoxicity test, cell adhesion test; Antibacterial assessment: Kirby–Bauer disc diffusion method or antibiotic sensitivity test and spread plate method.

  

Bone biology: bone architecture, collagen, osteoblasts, osteoclasts, etc; Protein mediated cell adhesion; Biomaterials for drug delivery, timed release materials; Blood compatible materials; Biomimetics

  

Introduction to tissue engineering; Applications of tissue engineering; Biomaterials world wide market, technology transfer and ethical issues; Standards for biomaterials and devices.

TEXTBOOKS

1.       Hench L. Larry, and Jones J., (Editors), Biomaterials, Artificial organs and Tissue Engineering, Woodhead Publishing Limited, 2005. 

 

2.        Hench L. Larry, & Wilson J., (Editors), An Introduction to Bioceramics, World Scientific, 1994.